Noémie Prébonnaud

Publications HAL

Article dans une revue (4 documents)

Noémie Prébonnaud, Alexia Chauzy, Claire Dahyot-Fizelier. Les infections neuroméningées associées aux soins liées aux dérivations ventriculaires externes. Anesthésie & Réanimation, 2026, 12 (3), pp.266-274. ⟨10.1016/j.anrea.2026.02.001⟩. ⟨hal-05684387⟩
Noémie Prébonnaud, Alexia Chauzy, Nicolas Grégoire, Claire Dahyot-Fizelier, Christophe Adier, et al.. A freely accessible, adaptable hollow-fiber setup to reproduce first-order absorption: illustration with linezolid cerebrospinal fluid pharmacokinetic data. Microbiology Spectrum, 2025, ⟨10.1128/spectrum.00051-25⟩. ⟨hal-05085650⟩
Gwenaëlle Mahieu, Laure Elens, Noémie Prébonnaud, Alexia Chauzy, Françoise van Bambeke. A hollow fiber infection model to study intracellular and extracellular antibiotic activity against Staphylococcus aureus. iScience, 2025, 28 (3), pp.112076. ⟨10.1016/j.isci.2025.112076⟩. ⟨hal-05136030⟩
Kévin Brunet, Cheikh Diop, Alexia Chauzy, Noémie Prébonnaud, Sandrine Marchand, et al.. Improved In Vitro Anti-Mucorales Activity and Cytotoxicity of Amphotericin B with a Pegylated Surfactant. Journal of Fungi, 2022, 8 (2), pp.121. ⟨10.3390/jof8020121⟩. ⟨hal-03615762⟩

Poster (3 documents)

Michael Burtin, Noémie Prébonnaud, Sandrine Marchand, Nicolas Grégoire, Claire Dahyot-Fizelier, et al.. Simulation-based prediction of pharmacokinetic/pharmacodynamic (PK/PD) index for linezolid to treat cerebral infections in critically ill patients. ESCMID global, Apr 2026, Munich, Germany. ⟨hal-05602892⟩
Michael Burtin, Noémie Prébonnaud, Sandrine Marchand, Nicolas Grégoire, Claire Dahyot-Fizelier, et al.. Simulation-based prediction of pharmacokinetic/pharmacodynamic (PK/PD) index for linezolid to treat cerebral infections in critically ill patients. 33rd PAGE meeting, Jun 2025, Thessalokini, Greece. . ⟨hal-05240779⟩
Noémie Prébonnaud, Alexia Chauzy, Christophe Adier, Isabelle Martin, Claire Dahyot-Fizelier, et al.. Impact of in vitro use of artificial cerebrospinal fluid compared to Mueller-Hinton broth on the efficacy of linezolid against Staphylococcus aureus in a hollow-fiber model. 34th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), Apr 2024, Barcelona, Spain. ⟨hal-04571091⟩

Thèse (1 document)

Noémie Prébonnaud. Etude pharmacocinétique/pharmacodynamique du linézolide utilisé dans le traitement des infections neuroméningées associées aux soins. Pharmacologie. Université de Poitiers, 2025. Français. ⟨NNT : 2025POIT1801⟩. ⟨tel-05555713⟩

Pré-publication, Document de travail (1 document)

Noémie Prébonnaud, Alexia Chauzy, Nicolas Grégoire, Claire Dahyot-Fizelier, Christophe Adier, et al.. A freely accessible, adaptable hollow-fiber setup to reproduce first-order absorption: illustration with linezolid cerebrospinal fluid pharmacokinetic data. 2025. ⟨hal-05030769⟩

Communication dans un congrès (3 documents)

Noémie Prebonnaud, Alexia Chauzy, Marie Dominique, Christophe Adier, Isabelle Martin, et al.. Linezolid and meropenem in vitro efficacy in artificial cerebrospinal fluid compared to Mueller-Hinton broth in hollow-fiber. Annual meeting of the International Society of Anti-Infective Pharmacology (ISAP Annual Meeting 2024), International Society of Anti-Infective Pharmacology (ISAP), Apr 2024, Barcelona, Spain. ⟨hal-05582701⟩
Noémie Prebonnaud, Alexia Chauzy, Claire Dahyot-Fizelier, Sandrine Marchand. Predicting antibacterial efficacy of linezolid on Staphylococcus aureus in cerebral infections using in vitro hollow fiber model and pharmacokinetic-pharmacodynamic modeling. 33rd ECCMID : : European Congress of Clinical Microbiology & Infectious Diseases, Apr 2023, Copenaghen, Denmark. ⟨hal-04142287⟩
Noémie Prébonnaud, Alexia Chauzy, Claire Dahyot-Fizelier, Sandrine Marchand. Pharmacocinétique-pharmacodynamie du linézolide sur Staphylococcus aureus par Hollow-Fiber. 42ème Réunion interdisciplinaire de chimiothérapie anti-infectieuse, Dec 2022, Paris, France. ⟨hal-05582729⟩

Short CV:

Dr. Noémie Prébonnaud (born 27.12.1995, France) is a Hospital-University Assistant at the University of Poitiers, School of Medicine and Pharmacy, in unit UMR 1070 « Pharmacology of Antimicrobial Agents » and at the Toxicology and Pharmacokinetics laboratory of the University Hospital of Poitiers.

She studied Pharmacy at the University of Poitiers and joined the unit UMR 1070 « Pharmacology of Antimicrobial Agents » in 2021 in order to perform her PhD, during which she investigated in vitro pharmacokinetic/pharmacodynamic (PK/PD) of linezolid for the treatment of healthcare-associated neuro-meningeal infections.

She is mostly interested in antibiotics PK/PD in the context of cerebral infections. She is familiar with in vitro experiments (hollow-fiber infection model, time-kill curves) and PK/PD modeling. She is currently optimizing the experimental conditions (developing an artificial CSF, miniaturizing the hollow fiber infection model) to carry out experiments that more closely mimic in vivo conditions.

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Noémie Prébonnaud

Publications HAL