We are glad to announce that 3 of our projects have been funded as part of the JPIAMR 14th call : Disrupting Drug Resistance Using Innovative Design (https://www.jpiamr.eu/calls/therapeutics-call-2022/#supported-projects) :

• Optimization and implementation of ceftazidime or ceftazidime-avibactam combined with fosfomycin against highly resistant gram-negative bacteria (CAVIFOS) – The aim of the project is to define and implement a rational dosing regimen for the combination of ceftazidime or ceftazidime-avibactam with fosfomycin against Enterobacterales, for more details click on the link above. The project is coordinated by Sandrine Marchand, in partnership with :
  • Sebastian Wicha, University of Hamburg, Germany
  • Jacob Moran-Gilad, Ben Gurion University of the Negev, Israel
  • Angela Huttner, University of Geneva / Geneva University Hospitals, Switzerland
  • Fernando Docobo-Perez, University of Sevilla / Hospital Virgen Macarena, Spain
  • Maddalena Giannella, IRCCS Azienda Ospedaliero/University Alma Mater Studiorum of Bologna, Italy
• Optimization of Antibiotic Combinations using Organoids for treatment of Mycobacterium abscessus infections (ACOMa) – The objective of the ACOMa project is to improve the treatment of patient by optimizing antibiotic combinations by implementing innovative approaches coupling the use of lung organoid with semi-mechanistic PK/PD models, for more details click on the link above. The project is coordinated by Julien Buyck, in partnership with :
  • Peter Sander, Universität Zürich, Switzerland
  • Céline Cougoule, Institute of Pharmacology and Structural Biology, France
  • Angela Huttner, University of Geneva / Geneva University Hospitals, Switzerland
  • Nicola Ivan Lore, Ospedale San Raffaele, Italy
  • Lucas Boeck, Basel university, Switzerland
• New Inhalation Formulations for Improved Delivery of Antimicrobials (APRINHA) – The project aims to develop an apramycin inhalation with high penetration, deposition, retention, and efficacy of drug, so as to more effectively cure pneumonia patients, for more details click on the link above. The project is coordinated by Sven Hobbie, University of Zurich, Switzerland, in partnership with :
  • Frédéric Tewes
  • Dorothee Winterberg, Fraunhofer Institute for Toxicology and Experimental Medicine, Germany
  • Iraida Loinaz, CIDETEC, Spain
  • Edgars Liepins, Latvian Institute of Organic Synthesis, Latvia
  • Anna Fureby, RISE Reaserch Institute of Sweden AB, Sweden
  • Per Gerde, Inhalation Sciences Sweden AB, Sweden