Inserm U1070 presents a strong activity in analytics to measure drug concentrations in various biological fluids (plasma, urine, broncho-alveoalar lavage, sputum, feces, …).
Consequently, a platform was developed in the lab which is run according to quality management rules and is awarded ISO 9001 certification since January 2014 (renewal october 2020).
The platform is composed of 2 HPLC (High Performance Liquid Chromatography) with UV or fluorescence detectors and 2 Liquid Chromatography coupled with mass spectometers in tandem (LC-MS/MS quattro Micro Api, Waters France and TQ 3500, Apllied Biosystems, France).
HPLC with UV and fluorescence detectors
Liquid Chromatography coupled with tandem mass spectometers
All samples are treated in an extraction room which provides all materials necessary to perform samples extraction (solvent cabinet, chemical hood, 2 systems for solid-liquid extraction, …).
We are able to dose more than 50 molecules among differentmatrix (like plasma, urine, feces, LCR, LBA and tissue) and different species (human, murines, porc, cows, goat, rabbit and monkey)