Que recherchez-vous ?
Un contenu sur ce site
Une personne sur l'annuaire
Une formation sur le catalogue
Un contenu sur ce site
Une personne sur l'annuaire
Une formation sur le catalogue
We are pleased to announce that Dr Chloé Jacquet will be participating in the 45th ANNUAL CONGRESS of the European Society of Mycobacteriology, Lisbon, Portugal on 22-25 June 2025.
On June 24, she will take part in session 8 on “Therapeutic strategies for NTM and TB Part 2”, where she will present the work she has done with Marine Emeret:
« Fidaxomicin, a potential new drug for combinatorial therapies against Mycobacterium abscessus ».
We are delighted to present our latest article:
« A freely accessible, adaptable hollow-fiber setup to reproduce first-order absorption: illustration with linezolid cerebrospinal fluid pharmacokinetic data » 🔗
🔎 What’s new?
We developed and validated a novel hollow-fiber setup that enables in vitro simulation of mono-compartmental pharmacokinetics with an absorption phase, requiring only the addition of a programmable infusion pump to the traditional experimental setup.
✅ Key Result
We successfully replicated cerebrospinal fluid concentrations of linezolid observed in intensive care unit patients.
💡Why it matters ?
This tool supports optimization of antibiotic dosing regimens by accurately simulating:
• Drug concentrations at infection sites
• Plasma concentrations after oral or other extravascular administration
🔧 Try It Yourself
The algorithm and setup are available in an open-source web application to facilitate the design of hollow-fiber experimental protocols. 🔗 Click here!
Actualités et événements
Actualités et événements
Actualités et événements
Actualités et événements
Actualités et événements
Actualités et événements